J Integr Med. 2018 May;16(3):199-207.
Noni (Morinda citrifolia L.) fruit juice delays immunosenescence in the lymphocytes in lymph nodes of old F344 rats.
Pratap UP, Priyanka HP, Ramanathan KR, Raman V, Hima L, Thyagarajan S.
Lymphocytes from young and old rats were treated in vitro with noni juice. Lymphocytes were also isolated from old rats that had been fed noni juice for 60 days. In both tests, noni juice increased the proliferation of lymphocytes and the production of immune system signaling molecules, IL-2 and IFN-γ. Expression of p-NF-κB p65 and p50 was also increased by noni juice ingestion. (original abstract available at https://www.ncbi.nlm.nih.gov/pubmed/29691190).