Hepatotoxicity and subchronic toxicity tests of Morinda citrifolia (noni) fruit.

The Journal of Toxicological Sciences 34(5):581-585. 2009.
Hepatotoxicity and subchronic toxicity tests of Morinda citrifolia (noni) fruit.
West BJ, Su CX, Jensen CJ.

Freeze-dried filtered noni fruit puree was not toxic to human liver cells. Further it did not cause histopathological changes or provide evidence of dose-responses in hematological and clinical chemistry measurements, including liver function tests, when fed to rats for 90 days. The no-observed-adverse-effect level (NOAEL) for freeze-dried noni fruit puree is greater than 6.86 g/kg body weight, equivalent to approximately 90 mL of noni fruit juice/kg. (original abstract available at https://www.ncbi.nlm.nih.gov/pubmed/19797868).