Glycative Stress Research 2017 Vol. 4 (1), pp. 67-70.
Inhibition of AGE-induced Melanogenesis in B16 Melanoma Cells by Iridoid-containing Plants.
Abe Y, Takabe W, Yagi M, Uwaya A, Isami F, Yonei Y.

Noni fruit, leaf and seed extracts inhibited melanin production without influencing cell proliferation in AGE-collagen-induced melanogenesis tests. The seed extract exhibited the most potent activity, suggesting that noni seeds may be a useful cosmetic material. (available online at