Morinda citrifolia Leaf Extract Enhances Osteogenic Differentiation Through Activation of Wnt/β-Catenin Signaling.

J Med Food. 2018 Jan;21(1):57-69.
Morinda citrifolia Leaf Extract Enhances Osteogenic Differentiation Through Activation of Wnt/β-Catenin Signaling.
Gu H, Boonanantanasarn K, Kang M, Kim I, Woo KM, Ryoo HM, Baek JH.

Noni leaf extract increased the activity of alkaline phosphatase (ALP) and expression of osteoblast differentiation markers. The extract also increased matrix mineralization of hPDL cells. These results suggest that noni leaf may enhance osteogenic differentiation. (original abstract available at https://www.ncbi.nlm.nih.gov/pubmed/28981378).